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Transcriptional regulation by trithorax-group proteins.

Kingston, Robert E Tamkun, John W

Published in Cold Spring Harbor perspectives in biology

The trithorax group of genes (trxG) was identified in mutational screens that examined developmental phenotypes and suppression of Polycomb mutant phenotypes. The protein products of these genes are primarily involved in gene activation, although some can also have repressive effects. There is no central function for these proteins. Some move nucle...

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