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Novel endogenous N-acyl amides activate TRPV1-4 receptors, BV-2 microglia, and are regulated in brain in an acute model ... PDF available through Get Fulltext Research

Raboune, Siham Stuart, Jordyn M. Leishman, Emma Takacs, Sara M. Rhodes, Brandon Basnet, Arjun Jameyfield, Evan McHugh, Douglas Widlanski, Theodore Bradshaw, Heather B. ...

Published in Frontiers in Cellular Neuroscience

A family of endogenous lipids, structurally analogous to the endogenous cannabinoid, N-arachidonoyl ethanolamine (Anandamide), and called N-acyl amides have emerged as a family of biologically active compounds at TRP receptors. N-acyl amides are constructed from an acyl group and an amine via an amide bond. This same structure can be modified by ch...

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