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Opposing activities of DRM and MES-4 tune gene expression and X-chromosome repression in Caenorhabditis elegans germ cel... PDF available through Get Fulltext Research

Tabuchi, Tomoko M Rechtsteiner, Andreas Strome, Susan Hagstrom, Kirsten A

Published in G3 (Bethesda, Md.)

During animal development, gene transcription is tuned to tissue-appropriate levels. Here we uncover antagonistic regulation of transcript levels in the germline of Caenorhabditis elegans hermaphrodites. The histone methyltransferase MES-4 (Maternal Effect Sterile-4) marks genes expressed in the germline with methylated lysine on histone H3 (H3K36m...

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