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UNC5C is required for spinal accessory motor neuron development.

Dillon, Ak Jevince, Ar Lindsay Hinck Ackerman, Sl Lu, X Tessier-Lavigne, M Kaprielian, Z

Published in Molecular and Cellular Neuroscience

In both invertebrates and vertebrates, UNC5 receptors facilitate chemorepulsion away from a Netrin source. Unlike most motor neurons in the embryonic vertebrate spinal cord, spinal accessory motor neuron (SACMN) cell bodies and their axons translocate along a dorsally directed trajectory away from the floor plate/ventral midline and toward the late...

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