Theranostic immunoliposomes for osteoarthritis
Published in Nanomedicine: Nanotechnology, Biology, and Medicine
Schematic diagram of antibody targeted immunoliposomes binding onto damaged cartilage. Antibodies to type II collagen are normally blocked from binding to the surface of the articular cartilage. Proteolytic enzymes secreted by resident chondrocytes, synoviocytes or infiltrating leukocytes degrade the surface proteins and allow access of the antibod...